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Apoptotic vesicles from macrophages exacerbate periodontal bone resorption in periodontitis via delivering miR-143-3p concentrating on Igfbp5 Junhong XiaoAnti-drug antibodies to sifalimumab were detected in below a person-fifth on the subjects across the sifalimumab dose teams. Anti-drug antibody titres didn't have an apparent effect on sifalimumab